Table S2
Ontology	Revigo cluster	Mean cluster structural coverage	Cluster members	Description	Mean structural coverage	#subVOGs	#Proteins
cellular_component
	1	0.2223	GO:0019867	outer membrane	0.2223	13	51
	2	0.1400	GO:0005576	extracellular region	0.1400	67	267
	3	0.0450	GO:0044383	host chromosome	0.0450	1	3
	4	0.1150	GO:0016020	membrane	0.1150	193	696
	5	0.1969	GO:0032991	macromolecular complex	0.1969	7	40
	6	0.2036	GO:0005575	cellular_component	0.2036	4461	17222
	7	0.1058	GO:0044219	host cell plasmodesma	0.1942	6	13
			GO:0044156	host cell junction	0.1776	11	30
			GO:0044386	integral to host endoplasmic reticulum membrane	0.0757	3	8
			GO:0020002	host cell plasma membrane	0.1627	82	361
			GO:0044175	host cell endosome membrane	0.0728	25	111
			GO:0044385	integral to membrane of host cell	0.1490	50	112
			GO:0044178	host cell Golgi membrane	0.1026	29	106
			GO:0044185	host cell late endosome membrane	0.0715	2	4
			GO:0044166	host cell endoplasmic reticulum lumen	0.0380	1	2
			GO:0044167	host cell endoplasmic reticulum membrane	0.1231	26	90
			GO:0044200	host cell nuclear membrane	0.0918	29	122
			GO:0044168	host cell rough endoplasmic reticulum	0.0100	1	3
	8	0.0370	GO:0046729	viral procapsid	0.0370	1	4
	9	0.1398	GO:0019012	virion	0.1398	57	261
	10	0.1562	GO:0044229	host cell periplasmic space	0.1673	3	31
			GO:0044094	host cell nuclear part	0.1450	1	2
	11	0.0655	GO:0039615	T=1 icosahedral viral capsid	0.1293	29	133
			GO:0039622	T=16 icosahedral viral capsid	0.0800	2	7
			GO:0039623	T=25 icosahedral viral capsid	0.0135	2	23
			GO:0039617	T=3 icosahedral viral capsid	0.1050	1	3
			GO:0039625	viral inner capsid	0.0060	1	4
			GO:0039620	T=7 icosahedral viral capsid	0.0478	6	90
			GO:0039624	viral outer capsid	0.0590	3	7
			GO:0039621	T=13 icosahedral viral capsid	0.0835	2	4
	12	0.0170	GO:0044228	host cell surface	0.0170	1	3
	13	0.2733	GO:0098021	viral capsid, decoration	0.2733	7	45
	14	0.2373	GO:0044425	membrane part	0.2373	3117	11330
	15	0.1580	GO:0009295	nucleoid	0.1580	1	7
	16	0.0604	GO:0019029	helical viral capsid	0.0604	11	50
	17	0.2015	GO:0044384	host outer membrane	0.2015	2	25
	18	0.1294	GO:0044172	host cell endoplasmic reticulum-Golgi intermediate compartment	0.2937	7	15
			GO:0044162	host cell cytoplasmic vesicle membrane	0.1537	47	104
			GO:0033646	host intracellular part	0.1239	598	2535
			GO:0033650	host cell mitochondrion	0.0850	1	8
			GO:0042025	host cell nucleus	0.1032	383	1752
			GO:0033647	host intracellular organelle	0.1065	410	1830
			GO:0033648	host intracellular membrane-bounded organelle	0.1067	409	1827
			GO:0044216	other organism cell	0.0886	19	79
			GO:0033643	host cell part	0.1268	771	3276
			GO:0044279	other organism membrane	0.1386	261	990
			GO:0030430	host cell cytoplasm	0.1347	228	1016
			GO:0033655	host cell cytoplasm part	0.1627	100	284
			GO:0044220	host cell perinuclear region of cytoplasm	0.2236	26	102
			GO:0044165	host cell endoplasmic reticulum	0.0145	2	7
			GO:0044177	host cell Golgi apparatus	0.1397	21	57
			GO:0044174	host cell endosome	0.0715	2	4
			GO:0044217	other organism part	0.1259	794	3382
	19	0.0816	GO:0044421	extracellular region part	0.0830	15	64
			GO:0031012	extracellular matrix	0.0702	6	24
			GO:0005615	extracellular space	0.0916	9	40
	20	0.1198	GO:0098025	virus tail, baseplate	0.2233	72	343
			GO:0019013	viral nucleocapsid	0.0830	41	165
			GO:0019028	viral capsid	0.1217	708	2896
			GO:0055036	virion membrane	0.1027	118	413
			GO:0019030	icosahedral viral capsid	0.1161	55	290
			GO:0019033	viral tegument	0.0815	56	218
			GO:0036338	viral membrane	0.1061	205	774
GO:0044423			virion part	0.1240	1080	4429
biological_process
	21	0.1944	GO:0050684	regulation of mRNA processing	0.1993	6	21
			GO:1903313	positive regulation of mRNA metabolic process	0.1920	10	28
			GO:0061013	regulation of mRNA catabolic process	0.1920	10	28
	22	0.1741	GO:0055114	oxidation-reduction process	0.1741	27	149
	23	0.2051	GO:0039667	viral entry into host cell via pilus retraction	0.3850	1	2
			GO:0052192	movement in environment of other organism involved in symbiotic interaction	0.1695	164	818
			GO:0051701	interaction with host	0.1581	463	1942
			GO:0050792	regulation of viral process	0.1709	39	169
			GO:0032897	negative regulation of viral transcription	0.1984	7	36
			GO:0075136	response to host	0.1362	98	335
			GO:0043901	negative regulation of multi-organism process	0.2835	15	72
			GO:0009405	pathogenesis	0.1358	32	137
			GO:0035890	exit from host	0.1857	128	613
			GO:0051828	entry into other organism involved in symbiotic interaction	0.1462	155	589
			GO:1903900	regulation of viral life cycle	0.3579	8	36
			GO:0016032	viral process	0.1337	1152	4827
	24	0.3115	GO:0018193	peptidyl-amino acid modification	0.3115	6	26
	25	0.1811	GO:0051726	regulation of cell cycle	0.1811	17	60
	26	0.1491	GO:0055086	nucleobase-containing small molecule metabolic process	0.1491	239	1460
	27	0.1306	GO:0006139	nucleobase-containing compound metabolic process	0.1306	1774	8662
	28	0.1708	GO:0040011	locomotion	0.1708	173	841
	29	0.1166	GO:0008202	steroid metabolic process	0.1166	5	26
	30	0.1744	GO:0048519	negative regulation of biological process	0.1744	175	646
	31	0.1201	GO:0022610	biological adhesion	0.1201	130	450
	32	0.1471	GO:0006266	DNA ligation	0.1471	11	55
	33	0.2740	GO:0045229	external encapsulating structure organization	0.2740	1	2
	34	0.3270	GO:0051174	regulation of phosphorus metabolic process	0.3270	2	5
	35	0.1719	GO:0034404	nucleobase-containing small molecule biosynthetic process	0.1919	18	67
			GO:0008652	cellular amino acid biosynthetic process	0.1654	27	96
			GO:0016053	organic acid biosynthetic process	0.1622	57	217
			GO:1901607	alpha-amino acid biosynthetic process	0.1681	25	81
	36	0.1367	GO:0071704	organic substance metabolic process	0.1367	2134	10355
	37	0.1210	GO:0044267	cellular protein metabolic process	0.1210	187	615
	38	0.1923	GO:0072522	purine-containing compound biosynthetic process	0.2313	10	54
			GO:0042278	purine nucleoside metabolic process	0.2110	2	5
			GO:0042451	purine nucleoside biosynthetic process	0.1690	1	2
			GO:0009150	purine ribonucleotide metabolic process	0.1413	4	20
			GO:0009119	ribonucleoside metabolic process	0.2088	4	13
	39	0.1541	GO:0006796	phosphate-containing compound metabolic process	0.1541	233	1407
			GO:0019637	organophosphate metabolic process	0.1541	233	1407
	40	0.1573	GO:0023051	regulation of signaling	0.1573	73	238
	41	0.1733	GO:0019439	aromatic compound catabolic process	0.1830	26	96
			GO:0044270	cellular nitrogen compound catabolic process	0.1830	26	96
			GO:0046700	heterocycle catabolic process	0.1769	27	105
			GO:0051603	proteolysis involved in cellular protein catabolic process	0.1638	4	12
			GO:0044265	cellular macromolecule catabolic process	0.1694	15	51
			GO:0043632	modification-dependent macromolecule catabolic process	0.1638	4	12
	42	0.0965	GO:0072593	reactive oxygen species metabolic process	0.0965	2	13
	43	0.0842	GO:0009653	anatomical structure morphogenesis	0.1063	3	11
			GO:0032989	cellular component morphogenesis	0.0620	1	5
	44	0.1157	GO:1902579	multi-organism localization	0.1157	111	626
	45	0.0995	GO:0007155	cell adhesion	0.0995	4	10
	46	0.0955	GO:0019083	viral transcription	0.1216	29	110
			GO:0039694	viral RNA genome replication	0.1125	306	997
			GO:0039686	bidirectional double-stranded viral DNA replication	0.0682	20	135
			GO:0039693	viral DNA genome replication	0.1120	70	353
			GO:0039696	RNA-templated viral transcription	0.1090	1	2
			GO:0075526	cap snatching	0.0280	1	2
			GO:0046782	regulation of viral transcription	0.1038	29	127
			GO:0039689	negative stranded viral RNA replication	0.1090	1	2
	47	0.3058	GO:0031365	N-terminal protein amino acid modification	0.3058	4	10
	48	0.1488	GO:0009262	deoxyribonucleotide metabolic process	0.1488	162	939
	49	0.1385	GO:0039664	lysis of host organelle involved in viral entry into host cell	0.1385	6	22
50	0.1817	GO:0019082	viral protein processing	0.1817	22	55
51	0.2020	GO:0007264	small GTPase mediated signal transduction	0.2020	1	2
52	0.1765	GO:0051186	cofactor metabolic process	0.1765	74	366
53	0.1324	GO:0034641	cellular nitrogen compound metabolic process	0.1324	1843	8915
54	0.0916	GO:0009225	nucleotide-sugar metabolic process	0.0916	5	38
55	0.1090	GO:0031638	zymogen activation	0.1090	1	6
56	0.0846	GO:0009141	nucleoside triphosphate metabolic process	0.1133	41	165
		GO:0009161	ribonucleoside monophosphate metabolic process	0.0608	12	67
		GO:0009142	nucleoside triphosphate biosynthetic process	0.0912	6	26
		GO:0046390	ribose phosphate biosynthetic process	0.0692	13	69
		GO:0009259	ribonucleotide metabolic process	0.0823	14	72
		GO:0009126	purine nucleoside monophosphate metabolic process	0.0715	2	15
		GO:0009152	purine ribonucleotide biosynthetic process	0.1040	3	17
57	0.1517	GO:0051259	protein oligomerization	0.1517	56	130
58	0.1675	GO:0039702	viral budding via host ESCRT complex	0.1870	2	4
		GO:0019072	viral genome packaging	0.1480	84	336
59	0.2150	GO:0007166	cell surface receptor signaling pathway	0.2150	1	2
60	0.0840	GO:0009411	response to UV	0.0840	2	7
61	0.1538	GO:0009263	deoxyribonucleotide biosynthetic process	0.1538	118	759
62	0.1842	GO:0036260	RNA capping	0.1842	15	52
63	0.3270	GO:1901184	regulation of ERBB signaling pathway	0.3270	2	5
64	0.1689	GO:0043900	regulation of multi-organism process	0.1689	40	171
65	0.2049	GO:0009235	cobalamin metabolic process	0.2885	4	13
		GO:0006778	porphyrin-containing compound metabolic process	0.2850	1	5
		GO:0015939	pantothenate metabolic process	0.1710	1	4
		GO:0042559	pteridine-containing compound biosynthetic process	0.1554	47	173
		GO:0033014	tetrapyrrole biosynthetic process	0.2204	7	28
		GO:0046654	tetrahydrofolate biosynthetic process	0.1563	46	170
		GO:0046653	tetrahydrofolate metabolic process	0.1579	47	172
66	0.1559	GO:0065008	regulation of biological quality	0.1559	83	391
67	0.0566	GO:0016042	lipid catabolic process	0.0566	7	28
68	0.0925	GO:0016072	rRNA metabolic process	0.1317	6	20
		GO:0008033	tRNA processing	0.0946	12	56
		GO:0006400	tRNA modification	0.0888	6	26
		GO:0034470	ncRNA processing	0.0915	13	58
		GO:0006364	rRNA processing	0.0540	1	2
		GO:0006399	tRNA metabolic process	0.0942	19	77
69	0.1226	GO:0034654	nucleobase-containing compound biosynthetic process	0.1303	694	3073
		GO:0032774	RNA biosynthetic process	0.1197	484	1764
		GO:0097659	nucleic acid-templated transcription	0.1179	446	1615
70	0.1482	GO:1901564	organonitrogen compound metabolic process	0.1482	636	3024
71	0.1656	GO:1901136	carbohydrate derivative catabolic process	0.1656	131	838
72	0.1219	GO:0043412	macromolecule modification	0.1219	229	809
73	0.1390	GO:0032502	developmental process	0.1390	4	14
74	0.1203	GO:0006996	organelle organization	0.1203	102	562
75	0.3430	GO:0006325	chromatin organization	0.3430	1	2
76	0.1465	GO:0050896	response to stimulus	0.1465	314	1488
77	0.2166	GO:0006313	transposition, DNA-mediated	0.2166	10	26
78	0.1553	GO:0065007	biological regulation	0.1553	483	1907
79	0.0589	GO:0034622	cellular macromolecular complex assembly	0.1274	8	26
		GO:0017004	cytochrome complex assembly	0.0060	1	9
		GO:0033108	mitochondrial respiratory chain complex assembly	0.0060	1	9
		GO:0070897	DNA-templated transcriptional preinitiation complex assembly	0.0938	5	12
		GO:0051260	protein homooligomerization	0.0612	6	19
80	0.0636	GO:0048878	chemical homeostasis	0.1207	3	14
		GO:0060249	anatomical structure homeostasis	0.0065	2	31
81	0.2370	GO:0048646	anatomical structure formation involved in morphogenesis	0.2370	1	3
82	0.0750	GO:0034248	regulation of cellular amide metabolic process	0.0750	1	12
83	0.1545	GO:0006793	phosphorus metabolic process	0.1545	235	1412
84	0.1190	GO:0031123	RNA 3'-end processing	0.1190	3	18
85	0.1829	GO:0007154	cell communication	0.1829	8	37
86	0.1453	GO:0002376	immune system process	0.1453	4	11
87	0.0958	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction	0.1279	22	69
		GO:0039523	suppression by virus of host RNA polymerase II activity	0.0280	1	2
		GO:0039724	suppression by virus of host IKBKE activity	0.1090	1	2
		GO:0039563	suppression by virus of host STAT1 activity	0.1183	3	7
88	0.2132	GO:0006457	protein folding	0.2132	18	91
89	0.1176	GO:0048522	positive regulation of cellular process	0.1311	59	201
		GO:0010942	positive regulation of cell death	0.0900	1	2
		GO:0031325	positive regulation of cellular metabolic process	0.1318	58	199
90	0.1640	GO:0009162	deoxyribonucleoside monophosphate metabolic process	0.1640	73	445
91	0.1582	GO:0046385	deoxyribose phosphate biosynthetic process	0.1582	84	484
92	0.1484	GO:0030162	regulation of proteolysis	0.1644	5	13
		GO:0032268	regulation of cellular protein metabolic process	0.1364	28	94
		GO:0031399	regulation of protein modification process	0.1445	24	74
93	0.0980	GO:0099018	restriction-modification system evasion by virus	0.0980	1	9
94	0.1755	GO:0006508	proteolysis	0.1755	27	98
95	0.1322	GO:0044260	cellular macromolecule metabolic process	0.1322	1554	7346
96	0.0731	GO:0098657	import into cell	0.0731	10	110
97	0.1536	GO:0060759	regulation of response to cytokine stimulus	0.1536	68	225
98	0.1392	GO:0008150	biological_process	0.1392	3435	16134
99	0.1148	GO:0070647	protein modification by small protein conjugation or removal	0.1148	6	22
100	0.1686	GO:0001505	regulation of neurotransmitter levels	0.1686	20	61
101	0.1197	GO:0009059	macromolecule biosynthetic process	0.1197	1019	4509
102	0.2727	GO:0008654	phospholipid biosynthetic process	0.4780	1	3
		GO:0044255	cellular lipid metabolic process	0.2132	5	12
		GO:0008610	lipid biosynthetic process	0.1768	6	29
		GO:0006644	phospholipid metabolic process	0.2228	4	10
103	0.1607	GO:0044092	negative regulation of molecular function	0.1859	43	146
		GO:0051336	regulation of hydrolase activity	0.1644	5	13
		GO:0051338	regulation of transferase activity	0.1445	24	74
		GO:0050790	regulation of catalytic activity	0.1479	29	87
104	0.0720	GO:0006421	asparaginyl-tRNA aminoacylation	0.0720	1	2
105	0.1750	GO:1901568	fatty acid derivative metabolic process	0.1750	1	2
106	0.1883	GO:0006402	mRNA catabolic process	0.3035	2	4
		GO:0034661	ncRNA catabolic process	0.1472	5	18
		GO:0009143	nucleoside triphosphate catabolic process	0.1410	2	4
		GO:0006397	mRNA processing	0.1926	19	76
		GO:0009166	nucleotide catabolic process	0.1993	13	53
		GO:0006401	RNA catabolic process	0.1919	7	22
		GO:0006308	DNA catabolic process	0.1358	4	17
		GO:0009264	deoxyribonucleotide catabolic process	0.1955	11	45
107	0.0230	GO:0048017	inositol lipid-mediated signaling	0.0230	1	3
108	0.1515	GO:0044262	cellular carbohydrate metabolic process	0.1515	2	6
109	0.1732	GO:0009069	serine family amino acid metabolic process	0.1732	21	64
110	0.1241	GO:0071840	cellular component organization or biogenesis	0.1241	243	994
111	0.1468	GO:0006310	DNA recombination	0.1468	208	1044
112	0.2480	GO:0009066	aspartate family amino acid metabolic process	0.2480	4	17
113	0.4793	GO:0006790	sulfur compound metabolic process	0.4793	4	12
114	0.1043	GO:0051641	cellular localization	0.1043	43	197
115	0.3058	GO:0006497	protein lipidation	0.3058	4	10
116	0.0180	GO:0006487	protein N-linked glycosylation	0.0180	1	4
117	0.1566	GO:0042558	pteridine-containing compound metabolic process	0.1566	49	178
118	0.1950	GO:1901571	fatty acid derivative transport	0.1950	2	4
119	0.1164	GO:0071702	organic substance transport	0.1164	18	109
120	0.1301	GO:0006259	DNA metabolic process	0.1301	1014	5301
121	0.2250	GO:0098003	viral tail assembly	0.2250	24	98
122	0.1778	GO:0016051	carbohydrate biosynthetic process	0.1778	4	10
123	0.0511	GO:0009226	nucleotide-sugar biosynthetic process	0.1118	4	16
		GO:0019673	GDP-mannose metabolic process	0.0175	2	26
		GO:0009298	GDP-mannose biosynthetic process	0.0240	1	4
124	0.1328	GO:0019438	aromatic compound biosynthetic process	0.1328	747	3278
125	0.0700	GO:0031343	positive regulation of cell killing	0.0900	1	2
		GO:0051715	cytolysis in other organism	0.0500	1	19
126	0.1353	GO:0006352	DNA-templated transcription, initiation	0.1353	35	140
127	0.0957	GO:0009628	response to abiotic stimulus	0.0957	3	9
128	0.1397	GO:0010506	regulation of autophagy	0.1397	46	149
129	0.0654	GO:0070085	glycosylation	0.0654	5	14
130	0.0180	GO:0009065	glutamine family amino acid catabolic process	0.0180	1	9
131	0.1519	GO:0006082	organic acid metabolic process	0.1519	73	274
132	0.0909	GO:0051248	negative regulation of protein metabolic process	0.0880	4	20
		GO:0052548	regulation of endopeptidase activity	0.0923	3	8
		GO:0045861	negative regulation of proteolysis	0.0923	3	8
133	0.1328	GO:0043170	macromolecule metabolic process	0.1328	1754	8370
134	0.0723	GO:0006289	nucleotide-excision repair	0.0723	4	13
135	0.1602	GO:0006541	glutamine metabolic process	0.1602	6	23
136	0.1322	GO:0006898	receptor-mediated endocytosis	0.1322	5	11
137	0.0170	GO:0005996	monosaccharide metabolic process	0.0170	1	11
138	0.1317	GO:0046483	heterocycle metabolic process	0.1317	1829	8871
139	0.1754	GO:0044283	small molecule biosynthetic process	0.1754	79	297
140	0.2065	GO:0046116	queuosine metabolic process	0.2065	2	8
141	0.1610	GO:0035821	modification of morphology or physiology of other organism	0.1610	228	810
142	0.3579	GO:0032879	regulation of localization	0.3579	8	36
143	0.1344	GO:0044271	cellular nitrogen compound biosynthetic process	0.1344	762	3324
144	0.1539	GO:1901657	glycosyl compound metabolic process	0.1622	20	138
		GO:1901137	carbohydrate derivative biosynthetic process	0.1456	139	860
145	0.1497	GO:0009605	response to external stimulus	0.1497	126	461
146	0.0750	GO:0010608	posttranscriptional regulation of gene expression	0.0750	1	12
147	0.2386	GO:0039678	viral genome ejection through host cell envelope	0.2386	34	187
148	0.1206	GO:0039514	suppression by virus of host JAK-STAT cascade	0.1206	24	86
149	0.0756	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	0.0756	5	24
150	0.1090	GO:0006431	methionyl-tRNA aminoacylation	0.1090	1	2
151	0.1397	GO:0009987	cellular process	0.1397	2291	10962
152	0.1655	GO:0043603	cellular amide metabolic process	0.1655	55	201
153	0.1536	GO:0006950	response to stress	0.1536	205	1106
154	0.2212	GO:0017006	protein-tetrapyrrole linkage	0.2212	5	26
155	0.1190	GO:0018298	protein-chromophore linkage	0.1190	1	2
156	0.1062	GO:0039654	fusion of virus membrane with host endosome membrane	0.1246	33	117
		GO:0019073	viral DNA genome packaging	0.1076	50	185
		GO:0019069	viral capsid assembly	0.1015	53	308
		GO:0019064	fusion of virus membrane with host plasma membrane	0.0663	39	143
		GO:0046765	viral budding from nuclear membrane	0.0918	12	61
		GO:0046755	viral budding	0.1226	25	94
		GO:0046760	viral budding from Golgi membrane	0.1290	7	20
157	0.1190	GO:0051606	detection of stimulus	0.1190	1	2
158	0.1327	GO:1901362	organic cyclic compound biosynthetic process	0.1327	753	3307
159	0.1973	GO:0002920	regulation of humoral immune response	0.2530	2	5
		GO:0002697	regulation of immune effector process	0.2530	2	5
		GO:0050690	regulation of defense response to virus by virus	0.1369	95	319
		GO:0002682	regulation of immune system process	0.1462	94	316
160	0.1146	GO:0006260	DNA replication	0.1146	516	2643
161	0.0687	GO:0009218	pyrimidine ribonucleotide metabolic process	0.0687	11	54
162	0.0901	GO:1902586	multi-organism intercellular transport	0.1116	36	205
		GO:0075519	microtubule-dependent intracellular transport of viral material	0.0673	23	93
		GO:0075733	intracellular transport of virus	0.0980	49	227
		GO:1902581	multi-organism cellular localization	0.1063	42	191
		GO:0075606	transport of viral material towards nucleus	0.0673	23	93
163	0.1377	GO:0006265	DNA topological change	0.1377	43	228
164	0.2995	GO:0042135	neurotransmitter catabolic process	0.4450	1	3
		GO:0042136	neurotransmitter biosynthetic process	0.1540	19	58
165	0.0480	GO:0043648	dicarboxylic acid metabolic process	0.0480	1	5
166	0.1790	GO:0072583	clathrin-dependent endocytosis	0.1790	1	2
167	0.1457	GO:0048518	positive regulation of biological process	0.1457	77	297
168	0.1116	GO:0051814	movement in other organism involved in symbiotic interaction	0.1116	36	205
169	0.1538	GO:1901135	carbohydrate derivative metabolic process	0.1538	362	2134
170	0.1318	GO:0006725	cellular aromatic compound metabolic process	0.1318	1830	8877
171	0.1950	GO:0015711	organic anion transport	0.1950	2	4
172	0.3430	GO:0031341	regulation of cell killing	0.3281	9	38
		GO:0031342	negative regulation of cell killing	0.3579	8	36
173	0.1198	GO:0016070	RNA metabolic process	0.1198	548	2031
174	0.2333	GO:0072521	purine-containing compound metabolic process	0.2333	11	57
175	0.1455	GO:0039687	viral DNA strand displacement replication	0.1455	2	4
176	0.1311	GO:0009894	regulation of catabolic process	0.1311	51	167
177	0.1764	GO:0009254	peptidoglycan turnover	0.2152	10	45
		GO:0030203	glycosaminoglycan metabolic process	0.1664	125	822
		GO:0006027	glycosaminoglycan catabolic process	0.1612	114	775
		GO:0006026	aminoglycan catabolic process	0.1629	120	793
178	0.1443	GO:0006974	cellular response to DNA damage stimulus	0.1443	171	959
179	0.1557	GO:0042398	cellular modified amino acid biosynthetic process	0.1557	48	177
180	0.2850	GO:0042440	pigment metabolic process	0.2850	1	5
181	0.1317	GO:1901360	organic cyclic compound metabolic process	0.1317	1836	8912
182	0.1614	GO:1901565	organonitrogen compound catabolic process	0.1614	125	815
183	0.1604	GO:0009056	catabolic process	0.1604	162	951
184	0.0828	GO:0006820	anion transport	0.1315	4	25
		GO:0034220	ion transmembrane transport	0.0340	1	15
185	0.2287	GO:0099046	clearance of foreign intracellular nucleic acids	0.3935	2	7
		GO:0098542	defense response to other organism	0.2288	17	75
		GO:0009620	response to fungus	0.1560	1	3
		GO:0052173	response to defenses of other organism involved in symbiotic interaction	0.1362	98	335
		GO:0009617	response to bacterium	0.2288	17	75
186	0.1187	GO:0034645	cellular macromolecule biosynthetic process	0.1187	979	4356
187	0.1735	GO:0051156	glucose 6-phosphate metabolic process	0.1735	2	13
188	0.1540	GO:0050794	regulation of cellular process	0.1525	410	1612
		GO:0050789	regulation of biological process	0.1555	457	1799
189	0.1400	GO:0006002	fructose 6-phosphate metabolic process	0.1400	1	7
190	0.1364	GO:0006807	nitrogen compound metabolic process	0.1364	2061	10074
191	0.1750	GO:0008217	regulation of blood pressure	0.1750	1	2
192	0.2848	GO:0051128	regulation of cellular component organization	0.2848	4	10
193	0.1973	GO:0051604	protein maturation	0.1973	18	66
194	0.1297	GO:0051202	phytochromobilin metabolic process	0.1297	3	15
195	0.1625	GO:0006040	amino sugar metabolic process	0.1625	31	96
196	0.1513	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	0.1513	83	497
197	0.1251	GO:0006629	lipid metabolic process	0.1251	31	117
198	0.1240	GO:0009112	nucleobase metabolic process	0.1240	1	3
199	0.1281	GO:0044249	cellular biosynthetic process	0.1281	1265	5912
200	0.0731	GO:0016192	vesicle-mediated transport	0.0731	10	110
201	0.2159	GO:0006518	peptide metabolic process	0.2670	1	2
		GO:0043604	amide biosynthetic process	0.1648	53	196
202	0.3270	GO:0010469	regulation of receptor activity	0.3270	2	5
203	0.1455	GO:0051246	regulation of protein metabolic process	0.1455	30	99
204	0.0680	GO:0015698	inorganic anion transport	0.0680	2	21
205	0.1537	GO:1901605	alpha-amino acid metabolic process	0.1688	29	99
		GO:0009064	glutamine family amino acid metabolic process	0.1399	7	32
		GO:0006520	cellular amino acid metabolic process	0.1523	39	138
206	0.0230	GO:0046486	glycerolipid metabolic process	0.0230	1	3
207	0.2320	GO:0006730	one-carbon metabolic process	0.2320	1	2
208	0.1190	GO:0033567	DNA replication, Okazaki fragment processing	0.1190	10	26
209	0.1583	GO:0010604	positive regulation of macromolecule metabolic process	0.1819	35	156
		GO:0010628	positive regulation of gene expression	0.1793	24	126
		GO:0009893	positive regulation of metabolic process	0.1465	76	295
		GO:0051254	positive regulation of RNA metabolic process	0.1708	16	58
		GO:1902680	positive regulation of RNA biosynthetic process	0.1355	6	30
		GO:0009891	positive regulation of biosynthetic process	0.1370	7	32
		GO:0051173	positive regulation of nitrogen compound metabolic process	0.1694	17	60
		GO:0051054	positive regulation of DNA metabolic process	0.1460	1	2
210	0.1492	GO:0044281	small molecule metabolic process	0.1492	316	1757
211	0.2598	GO:0006270	DNA replication initiation	0.2598	12	35
212	0.1469	GO:0072527	pyrimidine-containing compound metabolic process	0.1469	146	764
213	0.1218	GO:0032259	methylation	0.1218	33	157
214	0.1005	GO:0006979	response to oxidative stress	0.1005	2	6
215	0.4105	GO:0031163	metallo-sulfur cluster assembly	0.4105	2	7
216	0.3048	GO:0018126	protein hydroxylation	0.3048	4	21
217	0.2285	GO:0033013	tetrapyrrole metabolic process	0.2285	8	33
218	0.2716	GO:0009071	serine family amino acid catabolic process	0.4450	1	3
		GO:0009070	serine family amino acid biosynthetic process	0.1597	20	61
		GO:0019264	glycine biosynthetic process from serine	0.2320	1	2
		GO:0006563	L-serine metabolic process	0.2495	2	5
219	0.1564	GO:0009144	purine nucleoside triphosphate metabolic process	0.1690	1	2
		GO:1901293	nucleoside phosphate biosynthetic process	0.1507	161	1096
		GO:0009117	nucleotide metabolic process	0.1500	225	1384
		GO:0006753	nucleoside phosphate metabolic process	0.1499	227	1388
		GO:0090407	organophosphate biosynthetic process	0.1568	163	1101
		GO:0009199	ribonucleoside triphosphate metabolic process	0.1690	1	2
		GO:0009123	nucleoside monophosphate metabolic process	0.1494	85	512
220	0.1878	GO:0009308	amine metabolic process	0.1878	10	35
221	0.1778	GO:0005976	polysaccharide metabolic process	0.1778	4	10
222	0.0100	GO:0039665	permeabilization of host organelle membrane involved in viral entry into host cell	0.0100	1	3
223	0.1430	GO:0071897	DNA biosynthetic process	0.1430	35	177
224	0.2303	GO:0042737	drug catabolic process	0.2303	7	21
225	0.2031	GO:0016071	mRNA metabolic process	0.2031	21	80
226	0.0785	GO:0071103	DNA conformation change	0.1226	100	531
		GO:0006323	DNA packaging	0.1152	52	278
		GO:0032392	DNA geometric change	0.0696	5	25
		GO:0032200	telomere organization	0.0065	2	31
227	0.2650	GO:0006766	vitamin metabolic process	0.2650	5	17
228	0.1143	GO:0044419	interspecies interaction between organisms	0.1322	1197	5025
		GO:0019079	viral genome replication	0.1102	420	1514
		GO:0019058	viral life cycle	0.1287	37	148
		GO:0044403	symbiosis, encompassing mutualism through parasitism	0.1336	1153	4829
		GO:0019068	virion assembly	0.0839	28	144
		GO:0044764	multi-organism cellular process	0.0974	75	283
229	0.1943	GO:0044282	small molecule catabolic process	0.2315	2	12
		GO:0044248	cellular catabolic process	0.1901	105	491
		GO:0009057	macromolecule catabolic process	0.1613	138	854
230	0.1745	GO:0055085	transmembrane transport	0.1745	2	32
231	0.1198	GO:0051179	localization	0.1198	126	708
232	0.1616	GO:1901566	organonitrogen compound biosynthetic process	0.1616	191	1003
233	0.0960	GO:0009445	putrescine metabolic process	0.0960	1	4
234	0.0900	GO:0043902	positive regulation of multi-organism process	0.0900	1	2
235	0.1998	GO:0032196	transposition	0.1998	13	43
236	0.2239	GO:0099000	viral genome ejection through host cell envelope, contractile tail mechanism	0.2598	24	116
		GO:0099002	viral genome ejection through host cell envelope, short tail mechanism	0.1880	10	71
237	0.0560	GO:0030163	protein catabolic process	0.0560	3	10
238	0.2485	GO:0050865	regulation of cell activation	0.2485	2	7
239	0.1225	GO:0006413	translational initiation	0.1225	2	12
240	0.2069	GO:0097164	ammonium ion metabolic process	0.2069	7	25
241	0.1460	GO:0051716	cellular response to stimulus	0.1460	179	996
242	0.1563	GO:0009132	nucleoside diphosphate metabolic process	0.1563	6	15
243	0.1769	GO:1901361	organic cyclic compound catabolic process	0.1769	27	105
244	0.3579	GO:0040012	regulation of locomotion	0.3579	8	36
245	0.1325	GO:0009072	aromatic amino acid family metabolic process	0.1325	2	15
246	0.1339	GO:0072524	pyridine-containing compound metabolic process	0.1339	13	142
247	0.0770	GO:0007049	cell cycle	0.0770	3	9
248	0.1368	GO:0044237	cellular metabolic process	0.1368	2010	9679
249	0.1071	GO:0018143	nucleic acid-protein covalent cross-linking	0.1071	159	513
250	0.0877	GO:0009451	RNA modification	0.0877	7	30
251	0.1142	GO:0006261	DNA-dependent DNA replication	0.1142	121	382
252	0.3579	GO:0032409	regulation of transporter activity	0.3579	8	36
253	0.3225	GO:0042357	thiamine diphosphate metabolic process	0.8290	1	2
		GO:0006220	pyrimidine nucleotide metabolic process	0.1423	144	759
		GO:0006221	pyrimidine nucleotide biosynthetic process	0.1477	96	540
		GO:0072528	pyrimidine-containing compound biosynthetic process	0.1544	98	545
		GO:0000096	sulfur amino acid metabolic process	0.2670	1	3
		GO:0006213	pyrimidine nucleoside metabolic process	0.1690	1	2
		GO:0044272	sulfur compound biosynthetic process	0.5480	2	5
254	0.1758	GO:0009892	negative regulation of metabolic process	0.2108	44	150
		GO:0080134	regulation of response to stress	0.1416	90	304
		GO:0048585	negative regulation of response to stimulus	0.1440	92	309
		GO:0043066	negative regulation of apoptotic process	0.1606	8	21
		GO:0010629	negative regulation of gene expression	0.2194	41	142
		GO:0010941	regulation of cell death	0.1422	45	147
		GO:0060548	negative regulation of cell death	0.1432	13	32
		GO:0009890	negative regulation of biosynthetic process	0.2153	12	44
		GO:0051172	negative regulation of nitrogen compound metabolic process	0.1907	15	52
		GO:0031324	negative regulation of cellular metabolic process	0.1907	15	52
		GO:0045934	negative regulation of nucleobase-containing compound metabolic process	0.2280	11	32
		GO:0010648	negative regulation of cell communication	0.1536	68	225
		GO:0023057	negative regulation of signaling	0.1536	68	225
		GO:0048523	negative regulation of cellular process	0.1671	113	404
255	0.1569	GO:0006575	cellular modified amino acid metabolic process	0.1569	50	182
256	0.1300	GO:0051704	multi-organism process	0.1300	1258	5237
257	0.0923	GO:0043086	negative regulation of catalytic activity	0.0923	3	8
258	0.0989	GO:0061024	membrane organization	0.0989	73	262
259	0.1742	GO:0065009	regulation of molecular function	0.1742	68	223
260	0.1948	GO:1903311	regulation of mRNA metabolic process	0.1948	16	49
261	0.2271	GO:0001906	cell killing	0.2271	29	148
262	0.1950	GO:0046903	secretion	0.1950	2	4
263	0.1462	GO:0019692	deoxyribose phosphate metabolic process	0.1462	117	619
264	0.0963	GO:0035556	intracellular signal transduction	0.0793	3	8
		GO:0007165	signal transduction	0.1133	4	10
265	0.1499	GO:0009607	response to biotic stimulus	0.1499	115	410
266	0.1328	GO:0018130	heterocycle biosynthetic process	0.1328	746	3266
267	0.1705	GO:0005975	carbohydrate metabolic process	0.1705	32	116
268	0.1493	GO:0048583	regulation of response to stimulus	0.1493	99	329
269	0.0230	GO:0030258	lipid modification	0.0230	1	3
270	0.1124	GO:0006396	RNA processing	0.1124	83	374
271	0.0210	GO:0033036	macromolecule localization	0.0210	1	6
272	0.1279	GO:1903320	regulation of protein modification by small protein conjugation or removal	0.1279	22	69
273	0.1735	GO:0006739	NADP metabolic process	0.1735	2	13
274	0.0610	GO:0006428	isoleucyl-tRNA aminoacylation	0.0610	1	3
275	0.1353	GO:0071824	protein-DNA complex subunit organization	0.1353	6	14
276	0.1373	GO:0006304	DNA modification	0.1373	36	166
277	0.0587	GO:0009173	pyrimidine ribonucleoside monophosphate metabolic process	0.0587	10	52
278	0.0070	GO:0006420	arginyl-tRNA aminoacylation	0.0070	1	3
279	0.1932	GO:0030154	cell differentiation	0.2370	1	3
		GO:0048869	cellular developmental process	0.1495	2	8
280	0.2064	GO:0046753	non-lytic viral release	0.2064	7	15
281	0.1509	GO:0019222	regulation of metabolic process	0.1509	310	1195
282	0.1202	GO:0036211	protein modification process	0.1202	186	613
283	0.2038	GO:0072330	monocarboxylic acid biosynthetic process	0.2326	5	21
		GO:0006631	fatty acid metabolic process	0.1750	1	2
284	0.1544	GO:0006811	ion transport	0.1544	5	27
285	0.1103	GO:0009200	deoxyribonucleoside triphosphate metabolic process	0.1103	38	159
286	0.1498	GO:0015074	DNA integration	0.1498	123	688
287	0.2005	GO:0051821	dissemination or transmission of organism from other organism involved in symbiotic interaction	0.2005	6	17
288	0.1825	GO:0009991	response to extracellular stimulus	0.1829	8	37
		GO:0042330	taxis	0.1817	3	6
		GO:0071496	cellular response to external stimulus	0.1829	8	37
289	0.1123	GO:0015931	nucleobase-containing compound transport	0.1123	15	99
290	0.0210	GO:0042886	amide transport	0.0210	1	6
291	0.2859	GO:0019835	cytolysis	0.2859	61	313
292	0.1275	GO:0090304	nucleic acid metabolic process	0.1275	1542	7247
293	0.1735	GO:0006081	cellular aldehyde metabolic process	0.1735	2	13
294	0.1916	GO:0006370	7-methylguanosine mRNA capping	0.1916	14	48
295	0.1839	GO:0039644	suppression by virus of host NF-kappaB transcription factor activity	0.3324	5	10
		GO:0039656	modulation by virus of host gene expression	0.2151	27	94
		GO:0051818	disruption of cells of other organism involved in symbiotic interaction	0.2334	28	129
		GO:0044068	modulation by symbiont of host cellular process	0.1508	122	412
		GO:0019048	modulation by virus of host morphology or physiology	0.1635	180	687
		GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	0.2522	22	76
		GO:0052255	modulation by organism of defense response of other organism involved in symbiotic interaction	0.1416	90	304
		GO:0039548	suppression by virus of host IRF3 activity	0.1590	1	2
		GO:0044362	negative regulation of molecular function in other organism	0.1516	32	102
		GO:0051673	membrane disruption in other organism	0.1537	47	104
		GO:0044364	disruption of cells of other organism	0.2271	29	148
		GO:0052564	response to immune response of other organism involved in symbiotic interaction	0.1369	95	319
		GO:0052185	modification of structure of other organism involved in symbiotic interaction	0.1537	47	104
		GO:0051807	evasion or tolerance of defense response of other organism involved in symbiotic interaction	0.1369	95	319
		GO:0044359	modulation of molecular function in other organism	0.1416	53	169
		GO:0052490	negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction	0.1584	10	24
		GO:0044501	modulation of signal transduction in other organism	0.1536	68	225
		GO:0051833	suppression of defenses of other organism involved in symbiotic interaction	0.1416	90	304
		GO:0039648	modulation by virus of host protein ubiquitination	0.1657	27	79
		GO:0039579	suppression by virus of host ISG15 activity	0.3324	5	10
		GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	0.1615	227	791
296	0.0175	GO:0006560	proline metabolic process	0.0180	1	9
		GO:0009084	glutamine family amino acid biosynthetic process	0.0170	1	3
297	0.1053	GO:0051649	establishment of localization in cell	0.1043	43	197
		GO:0051169	nuclear transport	0.1063	42	191
298	0.1932	GO:0044036	cell wall macromolecule metabolic process	0.1932	72	369
299	0.3048	GO:0018197	peptidyl-aspartic acid modification	0.3048	4	21
300	0.3035	GO:0006109	regulation of carbohydrate metabolic process	0.3035	2	4
301	0.1230	GO:0006305	DNA alkylation	0.1230	32	153
		GO:0044728	DNA methylation or demethylation	0.1230	32	153
302	0.1282	GO:1901576	organic substance biosynthetic process	0.1282	1274	5950
303	0.1267	GO:0072525	pyridine-containing compound biosynthetic process	0.1267	11	129
		GO:0019674	NAD metabolic process	0.1267	11	129
304	0.3980	GO:0039666	virion attachment to host cell pilus	0.4110	2	4
		GO:0046813	receptor-mediated virion attachment to host cell	0.3850	1	2
305	0.1659	GO:0006022	aminoglycan metabolic process	0.1659	155	915
306	0.0620	GO:0002097	tRNA wobble base modification	0.0620	1	3
307	0.0230	GO:0016310	phosphorylation	0.0230	1	3
308	0.2253	GO:0008216	spermidine metabolic process	0.2253	6	21
309	0.1573	GO:0010646	regulation of cell communication	0.1573	73	238
310	0.2358	GO:0016539	intein-mediated protein splicing	0.3060	9	25
		GO:0030908	protein splicing	0.2804	10	28
		GO:0016485	protein processing	0.1997	17	64
		GO:0097428	protein maturation by iron-sulfur cluster transfer	0.1570	1	2
311	0.1950	GO:0015849	organic acid transport	0.1950	2	4
312	0.1950	GO:0006869	lipid transport	0.1950	2	4
313	0.0986	GO:0006284	base-excision repair	0.0986	14	57
314	0.0810	GO:0001510	RNA methylation	0.0810	1	4
315	0.0425	GO:0006298	mismatch repair	0.0425	4	10
316	0.2230	GO:0032787	monocarboxylic acid metabolic process	0.2230	6	23
317	0.1325	GO:0044531	modulation of programmed cell death in other organism	0.1325	34	112
318	0.1789	GO:0010207	photosystem II assembly	0.2010	1	3
		GO:0009772	photosynthetic electron transport in photosystem II	0.1569	12	90
319	0.2370	GO:0043934	sporulation	0.2370	1	3
320	0.1915	GO:0046349	amino sugar biosynthetic process	0.2060	2	5
		GO:0046348	amino sugar catabolic process	0.1945	6	18
		GO:0006047	UDP-N-acetylglucosamine metabolic process	0.2060	2	5
		GO:1901071	glucosamine-containing compound metabolic process	0.1594	29	91
321	0.2530	GO:0033865	nucleoside bisphosphate metabolic process	0.2530	1	3
322	0.1066	GO:0071705	nitrogen compound transport	0.1066	16	105
323	0.1095	GO:0042221	response to chemical	0.1095	4	22
324	0.0340	GO:0009372	quorum sensing	0.0340	1	2
325	0.1940	GO:1901659	glycosyl compound biosynthetic process	0.1940	3	10
326	0.1566	GO:0022607	cellular component assembly	0.1566	66	163
327	0.1287	GO:0009058	biosynthetic process	0.1287	1290	6001
328	0.1554	GO:0019725	cellular homeostasis	0.1564	60	297
		GO:0045454	cell redox homeostasis	0.1583	57	283
		GO:0042592	homeostatic process	0.1516	62	328
329	0.1385	GO:0008152	metabolic process	0.1385	2201	10701
330	0.2910	GO:0015979	photosynthesis	0.2910	2	5
331	0.1983	GO:0006353	DNA-templated transcription, termination	0.1983	3	9
332	0.4140	GO:0051301	cell division	0.4140	1	2
333	0.2462	GO:0006952	defense response	0.2462	19	82
334	0.0967	GO:0051052	regulation of DNA metabolic process	0.0967	38	150
335	0.1337	GO:0044238	primary metabolic process	0.1337	1923	9214
336	0.1175	GO:0008380	RNA splicing	0.1175	2	4
337	0.1954	GO:0006091	generation of precursor metabolites and energy	0.1954	13	92
338	0.1565	GO:0051188	cofactor biosynthetic process	0.1677	67	336
		GO:0006732	coenzyme metabolic process	0.1627	64	326
		GO:0006733	oxidoreduction coenzyme metabolic process	0.1339	13	142
		GO:0009108	coenzyme biosynthetic process	0.1616	60	308
339	0.1915	GO:0046434	organophosphate catabolic process	0.1915	15	57
340	0.1118	GO:0018142	protein-DNA covalent cross-linking	0.1204	36	104
		GO:0018144	RNA-protein covalent cross-linking	0.1032	123	409
341	0.2808	GO:0099045	viral extrusion	0.3850	1	2
		GO:0046761	viral budding from plasma membrane	0.1767	6	13
342	0.0937	GO:0019693	ribose phosphate metabolic process	0.0937	16	85
343	0.1938	GO:0060968	regulation of gene silencing	0.1938	18	96
344	0.1274	GO:0019538	protein metabolic process	0.1274	212	703
345	0.3058	GO:0043543	protein acylation	0.3058	4	10
346	0.1118	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	0.1118	39	161
347	0.0936	GO:0043038	amino acid activation	0.0936	7	21
348	0.1032	GO:0034660	ncRNA metabolic process	0.1032	25	97
349	0.1486	GO:0043933	macromolecular complex subunit organization	0.1486	64	156
350	0.1333	GO:0018904	ether metabolic process	0.1333	4	15
351	0.1535	GO:0010468	regulation of gene expression	0.1639	226	893
		GO:0080090	regulation of primary metabolic process	0.1536	252	962
		GO:0031323	regulation of cellular metabolic process	0.1463	288	1090
		GO:2000112	regulation of cellular macromolecule biosynthetic process	0.1411	211	827
		GO:1903506	regulation of nucleic acid-templated transcription	0.1504	173	668
		GO:0019219	regulation of nucleobase-containing compound metabolic process	0.1510	242	928
		GO:0051171	regulation of nitrogen compound metabolic process	0.1524	250	958
		GO:0009889	regulation of biosynthetic process	0.1516	232	901
		GO:0060255	regulation of macromolecule metabolic process	0.1563	270	1058
		GO:0051252	regulation of RNA metabolic process	0.1603	205	781
		GO:2001141	regulation of RNA biosynthetic process	0.1619	194	742
352	0.1726	GO:0017144	drug metabolic process	0.1726	53	165
molecular_function
	353	0.1687	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	0.1696	42	151
			GO:0004146	dihydrofolate reductase activity	0.1678	40	143
	354	0.2100	GO:0001067	regulatory region nucleic acid binding	0.2100	1	2
	355	0.1189	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	0.1397	106	596
			GO:0003968	RNA-directed 5'-3' RNA polymerase activity	0.1125	362	1224
			GO:0034061	DNA polymerase activity	0.1015	233	825
			GO:0097747	RNA polymerase activity	0.1187	468	1820
			GO:0003896	DNA primase activity	0.1221	24	249
	356	0.1190	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor	0.1190	1	2
	357	0.3140	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	0.3140	1	3
	358	0.1100	GO:0003690	double-stranded DNA binding	0.1100	26	116
	359	0.1190	GO:0048256	flap endonuclease activity	0.1190	10	26
	360	0.0950	GO:0019838	growth factor binding	0.0950	2	11
	361	0.2670	GO:0016412	serine O-acyltransferase activity	0.2670	1	3
			GO:0016413	O-acetyltransferase activity	0.2670	1	3
	362	0.1668	GO:0070566	adenylyltransferase activity	0.1668	8	46
	363	0.2085	GO:0016830	carbon-carbon lyase activity	0.2085	16	75
	364	0.1537	GO:0022838	substrate-specific channel activity	0.1537	47	104
	365	0.1199	GO:1901265	nucleoside phosphate binding	0.1199	1148	5694
	366	0.1523	GO:0003917	DNA topoisomerase type I activity	0.1797	11	39
			GO:0061505	DNA topoisomerase II activity	0.1250	31	185
	367	0.1578	GO:0008135	translation factor activity, RNA binding	0.1578	24	78
	368	0.0541	GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	0.0541	7	43
	369	0.1550	GO:0016722	oxidoreductase activity, oxidizing metal ions	0.1550	1	2
	370	0.1313	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	0.1862	5	15
			GO:0008168	methyltransferase activity	0.1309	334	1691
			GO:0008173	RNA methyltransferase activity	0.1080	89	356
			GO:0008170	N-methyltransferase activity	0.1093	103	452
			GO:0008171	O-methyltransferase activity	0.1377	40	144
			GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	0.1158	136	635
	371	0.1207	GO:0008199	ferric iron binding	0.1207	3	14
	372	0.0110	GO:0044389	ubiquitin-like protein ligase binding	0.0110	1	3
	373	0.1223	GO:0035639	purine ribonucleoside triphosphate binding	0.1223	944	4692
	374	0.2016	GO:0005521	lamin binding	0.2016	5	13
	375	0.1535	GO:0015318	inorganic solute uptake transmembrane transporter activity	0.1535	50	114
	376	0.1817	GO:0001653	peptide receptor activity	0.1817	3	6
	377	0.1798	GO:0019904	protein domain specific binding	0.1798	18	62
	378	0.3652	GO:0004788	thiamine diphosphokinase activity	0.8290	1	2
			GO:0004749	ribose phosphate diphosphokinase activity	0.1525	11	100
			GO:0003848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	0.1140	1	3
	379	0.2057	GO:0016410	N-acyltransferase activity	0.2427	7	20
			GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	0.1975	15	42
			GO:0008080	N-acetyltransferase activity	0.2060	2	5
			GO:0016407	acetyltransferase activity	0.1768	4	13
	380	0.1199	GO:0003723	RNA binding	0.1199	484	1683
	381	0.1750	GO:0004666	prostaglandin-endoperoxide synthase activity	0.1750	1	2
	382	0.1090	GO:0004825	methionine-tRNA ligase activity	0.1090	1	2
	383	0.0240	GO:0016866	intramolecular transferase activity	0.0240	1	4
	384	0.2456	GO:0051540	metal cluster binding	0.2456	32	150
	385	0.0160	GO:0004089	carbonate dehydratase activity	0.0160	1	14
	386	0.1563	GO:0050145	nucleoside phosphate kinase activity	0.1563	6	15
	387	0.2340	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	0.2340	6	28
	388	0.0150	GO:0031072	heat shock protein binding	0.0150	2	7
	389	0.0170	GO:0004345	glucose-6-phosphate dehydrogenase activity	0.0170	1	11
	390	0.1675	GO:0070548	L-glutamine aminotransferase activity	0.1675	2	8
	391	0.1566	GO:0004518	nuclease activity	0.1624	605	2349
			GO:0042578	phosphoric ester hydrolase activity	0.1508	53	226
	392	0.1220	GO:0030554	adenyl nucleotide binding	0.1220	941	4665
	393	0.0563	GO:0008417	fucosyltransferase activity	0.0563	4	11
	394	0.1308	GO:0004550	nucleoside diphosphate kinase activity	0.1690	1	2
			GO:0004138	deoxyguanosine kinase activity	0.0920	1	2
			GO:0004797	thymidine kinase activity	0.1339	39	191
			GO:0019206	nucleoside kinase activity	0.1262	48	220
GO:0019136			deoxynucleoside kinase activity	0.1329	40	193
395	0.1590	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	0.1590	1	3
396	0.0756	GO:0008829	dCTP deaminase activity	0.0756	5	24
397	0.1923	GO:0016769	transferase activity, transferring nitrogenous groups	0.1923	3	29
398	0.1141	GO:0047429	nucleoside-triphosphate diphosphatase activity	0.1141	36	158
399	0.1292	GO:0005515	protein binding	0.1292	118	440
400	0.1391	GO:0003676	nucleic acid binding	0.1391	2430	10776
401	0.0887	GO:0003924	GTPase activity	0.0887	3	10
402	0.0180	GO:0003830	beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	0.0180	1	4
403	0.1200	GO:0036094	small molecule binding	0.1200	1191	5881
404	0.2353	GO:0070001	aspartic-type peptidase activity	0.2353	6	16
405	0.0380	GO:0008172	S-methyltransferase activity	0.0380	1	2
406	0.1703	GO:0016798	hydrolase activity, acting on glycosyl bonds	0.1703	127	586
407	0.2228	GO:0016987	sigma factor activity	0.2228	4	14
408	0.2016	GO:0016778	diphosphotransferase activity	0.2016	13	105
409	0.0450	GO:0031127	alpha-(1,2)-fucosyltransferase activity	0.0450	2	6
410	0.1843	GO:0016651	oxidoreductase activity, acting on NAD(P)H	0.1843	3	10
411	0.2038	GO:0000217	DNA secondary structure binding	0.2038	4	16
412	0.1520	GO:0008324	cation transmembrane transporter activity	0.1745	2	4
		GO:0015075	ion transmembrane transporter activity	0.1546	49	108
		GO:0015077	monovalent inorganic cation transmembrane transporter activity	0.1770	1	2
		GO:0022804	active transmembrane transporter activity	0.1020	1	6
413	0.1223	GO:0017076	purine nucleotide binding	0.1223	944	4692
414	0.2151	GO:0004857	enzyme inhibitor activity	0.3028	4	17
		GO:0030234	enzyme regulator activity	0.1299	14	67
		GO:0061134	peptidase regulator activity	0.2125	2	12
415	0.1303	GO:0019205	nucleobase-containing compound kinase activity	0.1303	55	237
416	0.2375	GO:0043364	catalysis of free radical formation	0.2375	15	90
417	0.1945	GO:0004568	chitinase activity	0.1945	6	18
418	0.1067	GO:0043177	organic acid binding	0.1067	29	113
419	0.0390	GO:0008309	double-stranded DNA exodeoxyribonuclease activity	0.0390	1	5
420	0.1740	GO:0020037	heme binding	0.1740	7	19
421	0.0532	GO:0004180	carboxypeptidase activity	0.0790	2	9
		GO:0070008	serine-type exopeptidase activity	0.0467	3	6
		GO:0008235	metalloexopeptidase activity	0.0340	1	7
422	0.1661	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	0.1661	43	160
423	0.1442	GO:0003916	DNA topoisomerase activity	0.1442	44	230
424	0.1297	GO:0016636	oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor	0.1297	3	15
425	0.2020	GO:0051020	GTPase binding	0.2020	1	2
426	0.0760	GO:0016835	carbon-oxygen lyase activity	0.0760	3	41
427	0.1872	GO:0004040	amidase activity	0.1872	9	30
428	0.1425	GO:0019239	deaminase activity	0.1425	21	110
429	0.2133	GO:0019001	guanyl nucleotide binding	0.2133	3	27
430	0.1317	GO:0016741	transferase activity, transferring one-carbon groups	0.1317	340	1709
431	0.1540	GO:0005102	receptor binding	0.1540	15	42
432	0.0603	GO:0051082	unfolded protein binding	0.0603	4	11
433	0.1276	GO:0009008	DNA-methyltransferase activity	0.1276	49	284
434	0.0700	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	0.0700	1	2
435	0.0572	GO:0046812	host cell surface binding	0.0572	14	53
436	0.0390	GO:0008409	5'-3' exonuclease activity	0.0390	1	5
437	0.1352	GO:0004132	dCMP deaminase activity	0.1661	15	84
		GO:0019238	cyclohydrolase activity	0.1176	8	32
		GO:0004000	adenosine deaminase activity	0.1220	1	2
438	0.1435	GO:0008094	DNA-dependent ATPase activity	0.1435	66	465
439	0.1148	GO:0019842	vitamin binding	0.1148	33	163
440	0.1240	GO:0016743	carboxyl- or carbamoyltransferase activity	0.1240	1	3
441	0.1110	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	0.1110	1	2
442	0.1044	GO:0016773	phosphotransferase activity, alcohol group as acceptor	0.0905	89	402
		GO:0016301	kinase activity	0.1183	195	838
443	0.2885	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	0.2885	4	13
444	0.0805	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	0.0805	2	19
445	0.1102	GO:0009007	site-specific DNA-methyltransferase (adenine-specific) activity	0.1352	39	239
		GO:0015667	site-specific DNA-methyltransferase (cytosine-N4-specific) activity	0.0996	5	17
		GO:0003886	DNA (cytosine-5-)-methyltransferase activity	0.0958	5	28
446	0.2886	GO:0051537	2 iron, 2 sulfur cluster binding	0.3458	5	17
		GO:0051539	4 iron, 4 sulfur cluster binding	0.2314	16	92
447	0.1725	GO:0043565	sequence-specific DNA binding	0.1725	239	929
448	0.1380	GO:0004588	orotate phosphoribosyltransferase activity	0.1380	1	2
449	0.1999	GO:0015666	restriction endodeoxyribonuclease activity	0.3935	2	7
		GO:0008855	exodeoxyribonuclease VII activity	0.1673	3	14
		GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.1555	112	412
		GO:0004520	endodeoxyribonuclease activity	0.1767	99	355
		GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.1714	86	289
		GO:0004529	exodeoxyribonuclease activity	0.1353	4	19
450	0.1555	GO:0005509	calcium ion binding	0.1555	2	5
451	0.1622	GO:0016657	oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor	0.2065	2	8
		GO:0003954	NADH dehydrogenase activity	0.1400	1	2
		GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	0.1400	1	2
452	0.1084	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	0.1084	16	78
453	0.1900	GO:0008933	lytic transglycosylase activity	0.2610	1	2
		GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	0.1163	47	422
		GO:0003796	lysozyme activity	0.1928	67	353
454	0.1720	GO:0070403	NAD+ binding	0.1720	6	26
455	0.0720	GO:0004816	asparagine-tRNA ligase activity	0.0720	1	2
456	0.0612	GO:1990837	sequence-specific double-stranded DNA binding	0.0786	14	71
		GO:0030983	mismatched DNA binding	0.0437	3	7
457	0.2080	GO:0003729	mRNA binding	0.2080	2	6
458	0.0830	GO:0016997	alpha-sialidase activity	0.0830	10	36
459	0.1190	GO:0003724	RNA helicase activity	0.1288	170	511
		GO:0003678	DNA helicase activity	0.1168	52	559
		GO:0070035	purine NTP-dependent helicase activity	0.1113	70	287
460	0.2137	GO:0101005	ubiquitinyl hydrolase activity	0.2137	11	32
461	0.2670	GO:0016801	hydrolase activity, acting on ether bonds	0.2670	1	2
462	0.1557	GO:0003937	IMP cyclohydrolase activity	0.2320	2	5
		GO:0003933	GTP cyclohydrolase activity	0.0795	6	27
463	0.1424	GO:0043169	cation binding	0.1424	462	2122
464	0.1198	GO:0030545	receptor regulator activity	0.1198	11	33
465	0.1943	GO:0005215	transporter activity	0.1943	87	293
466	0.0898	GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	0.0898	5	21
467	0.1321	GO:0004386	helicase activity	0.1321	360	1656
468	0.2838	GO:0051213	dioxygenase activity	0.2838	9	34
469	0.0340	GO:0042301	phosphate ion binding	0.0340	1	15
470	0.0607	GO:0030337	DNA polymerase processivity factor activity	0.0607	10	50
471	0.1735	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	0.1735	2	13
472	0.1425	GO:0004222	metalloendopeptidase activity	0.1425	15	54
473	0.1595	GO:0004532	exoribonuclease activity	0.3015	6	13
		GO:0004523	RNA-DNA hybrid ribonuclease activity	0.1011	19	88
		GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.2350	10	32
		GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	0.1032	27	125
		GO:0008408	3'-5' exonuclease activity	0.1700	38	144
		GO:0032296	double-stranded RNA-specific ribonuclease activity	0.1083	8	37
		GO:0004521	endoribonuclease activity	0.0976	30	131
474	0.0750	GO:0030597	RNA glycosylase activity	0.0750	1	12
475	0.2208	GO:0008889	glycerophosphodiester phosphodiesterase activity	0.2208	4	23
476	0.0610	GO:0004822	isoleucine-tRNA ligase activity	0.0610	1	3
477	0.2422	GO:0004045	aminoacyl-tRNA hydrolase activity	0.2422	5	26
478	0.1108	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	0.1108	52	334
479	0.1598	GO:0004536	deoxyribonuclease activity	0.1796	108	391
		GO:0004527	exonuclease activity	0.1677	107	390
		GO:0004519	endonuclease activity	0.1602	446	1702
		GO:0004540	ribonuclease activity	0.1316	36	144
480	0.1239	GO:0030246	carbohydrate binding	0.1239	35	130
481	0.1736	GO:0070851	growth factor receptor binding	0.3270	2	5
		GO:0001664	G-protein coupled receptor binding	0.1453	4	11
		GO:0005126	cytokine receptor binding	0.1453	4	11
		GO:0008083	growth factor activity	0.1053	7	22
		GO:0005125	cytokine activity	0.1453	4	11
482	0.0180	GO:0004657	proline dehydrogenase activity	0.0180	1	9
483	0.1865	GO:0016875	ligase activity, forming carbon-oxygen bonds	0.1899	14	48
		GO:0016879	ligase activity, forming carbon-nitrogen bonds	0.1831	19	101
484	0.1623	GO:0050797	thymidylate synthase (FAD) activity	0.1874	39	295
		GO:0004799	thymidylate synthase activity	0.1371	34	150
485	0.0210	GO:0003952	NAD+ synthase (glutamine-hydrolyzing) activity	0.0210	1	4
486	0.1297	GO:0050897	cobalt ion binding	0.1297	3	15
487	0.0070	GO:0004814	arginine-tRNA ligase activity	0.0070	1	3
488	0.2253	GO:0004014	adenosylmethionine decarboxylase activity	0.2253	6	21
489	0.1343	GO:0016298	lipase activity	0.1343	3	7
490	0.2510	GO:0051219	phosphoprotein binding	0.2510	1	4
491	0.0850	GO:0008373	sialyltransferase activity	0.0850	1	3
492	0.1167	GO:0004484	mRNA guanylyltransferase activity	0.1495	13	50
		GO:0008193	tRNA guanylyltransferase activity	0.0840	3	13
493	0.1426	GO:0046872	metal ion binding	0.1426	461	2119
494	0.0250	GO:0016977	chitosanase activity	0.0250	1	5
495	0.1950	GO:0004623	phospholipase A2 activity	0.1950	2	4
496	0.1781	GO:0009055	electron carrier activity	0.1781	55	318
497	0.1695	GO:0008374	O-acyltransferase activity	0.1695	2	5
498	0.1621	GO:0061783	peptidoglycan muralytic activity	0.1621	115	777
499	0.1725	GO:0048037	cofactor binding	0.1725	162	840
500	0.0647	GO:0019784	NEDD8-specific protease activity	0.0647	3	16
501	0.1582	GO:0000287	magnesium ion binding	0.1582	61	356
502	0.1604	GO:0016788	hydrolase activity, acting on ester bonds	0.1604	703	2742
503	0.2062	GO:0022803	passive transmembrane transporter activity	0.2062	66	215
504	0.0433	GO:0004722	protein serine/threonine phosphatase activity	0.0433	3	9
505	0.1065	GO:0019899	enzyme binding	0.1065	2	5
506	0.0170	GO:0016880	acid-ammonia (or amide) ligase activity	0.0170	1	3
507	0.1190	GO:1990817	RNA adenylyltransferase activity	0.1190	3	18
508	0.0720	GO:0033170	protein-DNA loading ATPase activity	0.0720	1	2
509	0.2158	GO:0016829	lyase activity	0.2158	37	188
510	0.1092	GO:0008174	mRNA methyltransferase activity	0.1092	87	351
511	0.2480	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity	0.2480	4	17
512	0.1237	GO:0097367	carbohydrate derivative binding	0.1237	988	4867
513	0.0260	GO:0004602	glutathione peroxidase activity	0.0260	1	4
514	0.1581	GO:0016776	phosphotransferase activity, phosphate group as acceptor	0.1581	7	17
515	0.1982	GO:0008242	omega peptidase activity	0.3015	6	13
		GO:0004177	aminopeptidase activity	0.0950	1	2
516	0.0610	GO:0002161	aminoacyl-tRNA editing activity	0.0610	1	3
517	0.1823	GO:0052689	carboxylic ester hydrolase activity	0.1823	10	40
518	0.1435	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	0.1435	61	291
519	0.2010	GO:0016838	carbon-oxygen lyase activity, acting on phosphates	0.2010	1	5
520	0.1404	GO:0003824	catalytic activity	0.1404	3506	16251
521	0.1590	GO:0030165	PDZ domain binding	0.1590	1	2
522	0.3048	GO:0004597	peptide-aspartate beta-dioxygenase activity	0.3048	4	21
523	0.1807	GO:0008079	translation termination factor activity	0.2310	1	5
		GO:0003746	translation elongation factor activity	0.1776	11	38
		GO:0003743	translation initiation factor activity	0.1336	12	35
524	0.1316	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.1356	29	142
		GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	0.1277	56	452
525	0.1143	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.1143	12	65
526	0.0430	GO:0016882	cyclo-ligase activity	0.0430	1	13
527	0.1043	GO:0039660	structural constituent of virion	0.1043	4	13
528	0.0640	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	0.0640	1	10
529	0.1129	GO:0008998	ribonucleoside-triphosphate reductase activity	0.1202	19	112
		GO:0061731	ribonucleoside-diphosphate reductase activity	0.1055	33	222
530	0.1444	GO:0008238	exopeptidase activity	0.1835	12	30
		GO:0004175	endopeptidase activity	0.1326	273	931
		GO:0008237	metallopeptidase activity	0.1374	19	68
		GO:0070011	peptidase activity, acting on L-amino acid peptides	0.1240	348	1195
531	0.0960	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	0.0960	1	4
532	0.1740	GO:0008962	phosphatidylglycerophosphatase activity	0.1740	1	2
533	0.4450	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	0.4450	1	3
534	0.1233	GO:0016740	transferase activity	0.1233	1378	5826
535	0.0653	GO:0019787	ubiquitin-like protein transferase activity	0.0653	7	27
536	0.1166	GO:0016772	transferase activity, transferring phosphorus-containing groups	0.1166	986	3864
537	0.1516	GO:0016874	ligase activity	0.1516	126	675
538	0.2530	GO:0001848	complement binding	0.2530	2	5
539	0.2117	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	0.2320	2	5
		GO:0004372	glycine hydroxymethyltransferase activity	0.2320	1	2
		GO:0003864	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	0.1710	1	4
540	0.2740	GO:0015929	hexosaminidase activity	0.2740	1	2
541	0.2166	GO:0004803	transposase activity	0.2166	10	26
542	0.1455	GO:0003697	single-stranded DNA binding	0.1455	95	777
543	0.4385	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	0.4385	2	4
544	0.1560	GO:0016757	transferase activity, transferring glycosyl groups	0.1560	47	247
545	0.1640	GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	0.1640	73	445
546	0.0803	GO:0008565	protein transporter activity	0.0803	6	30
547	0.1244	GO:0016817	hydrolase activity, acting on acid anhydrides	0.1244	621	2833
548	0.1383	GO:0005488	binding	0.1383	3383	15711
549	0.1590	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	0.1590	4	17
550	0.1670	GO:0005507	copper ion binding	0.1670	4	22
551	0.1475	GO:0019955	cytokine binding	0.1475	4	17
552	0.1557	GO:0019783	ubiquitin-like protein-specific protease activity	0.1818	14	48
		GO:0004197	cysteine-type endopeptidase activity	0.1297	192	566
553	0.1621	GO:0001883	purine nucleoside binding	0.2133	3	27
		GO:0032553	ribonucleotide binding	0.1226	948	4728
		GO:0001882	nucleoside binding	0.1505	13	71
554	0.1380	GO:0004150	dihydroneopterin aldolase activity	0.1380	1	3
555	0.1108	GO:0008134	transcription factor binding	0.1108	4	10
556	0.2574	GO:0019107	myristoyltransferase activity	0.2574	5	15
557	0.0980	GO:0046527	glucosyltransferase activity	0.0980	1	9
558	0.1197	GO:0008234	cysteine-type peptidase activity	0.1197	258	798
559	0.1417	GO:0016886	ligase activity, forming phosphoric ester bonds	0.1417	74	420
560	0.2028	GO:0022857	transmembrane transporter activity	0.2028	81	263
561	0.1447	GO:0016787	hydrolase activity	0.1447	1867	8429
562	0.0665	GO:0004176	ATP-dependent peptidase activity	0.0665	2	6
563	0.1569	GO:0045156	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	0.1569	12	90
564	0.3930	GO:0060703	deoxyribonuclease inhibitor activity	0.3930	2	5
565	0.1383	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.1383	89	604
566	0.0170	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	0.0170	1	4
567	0.1373	GO:1901363	heterocyclic compound binding	0.1373	2999	14020
568	0.2670	GO:0003735	structural constituent of ribosome	0.2670	1	2
569	0.1332	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	0.1332	40	156
570	0.1564	GO:0008270	zinc ion binding	0.1564	147	788
571	0.0885	GO:0003727	single-stranded RNA binding	0.0885	2	4
572	0.1061	GO:0004674	protein serine/threonine kinase activity	0.1234	21	76
		GO:0004672	protein kinase activity	0.0888	86	391
573	0.1658	GO:1901505	carbohydrate derivative transporter activity	0.1658	9	32
574	0.1365	GO:0008233	peptidase activity	0.1365	410	1470
575	0.0175	GO:0008194	UDP-glycosyltransferase activity	0.0175	2	8
576	0.1060	GO:0048029	monosaccharide binding	0.1060	28	110
577	0.1494	GO:0008081	phosphoric diester hydrolase activity	0.1792	5	26
		GO:0016791	phosphatase activity	0.1479	48	200
		GO:0004721	phosphoprotein phosphatase activity	0.1212	26	109
578	0.1373	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity	0.1373	10	125
579	0.2580	GO:0016860	intramolecular oxidoreductase activity	0.2580	1	2
580	0.1476	GO:0016491	oxidoreductase activity	0.1476	344	1780
581	0.2890	GO:0004497	monooxygenase activity	0.2890	4	8
582	0.1213	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	0.1817	104	483
		GO:0019104	DNA N-glycosylase activity	0.0994	13	54
		GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	0.0829	19	92
583	0.1421	GO:0005506	iron ion binding	0.1421	38	144
584	0.1166	GO:0016229	steroid dehydrogenase activity	0.1166	5	26
585	0.1305	GO:0043167	ion binding	0.1305	1409	7029
586	0.1400	GO:0019200	carbohydrate kinase activity	0.1400	1	7
587	0.2850	GO:0004392	heme oxygenase (decyclizing) activity	0.2850	1	5
588	0.1932	GO:0016746	transferase activity, transferring acyl groups	0.1932	17	46
589	0.1472	GO:0008061	chitin binding	0.1472	25	78
590	0.1303	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	0.1303	3	10
591	0.0130	GO:0004629	phospholipase C activity	0.0130	1	3
592	0.0318	GO:0031423	hexon binding	0.0318	6	46
593	0.1658	GO:0015932	nucleobase-containing compound transmembrane transporter activity	0.1658	9	32
594	0.1500	GO:0003972	RNA ligase (ATP) activity	0.1942	25	129
		GO:0003911	DNA ligase (NAD+) activity	0.1489	7	38
		GO:0003909	DNA ligase activity	0.1196	42	247
		GO:0008452	RNA ligase activity	0.1708	32	173
		GO:0003910	DNA ligase (ATP) activity	0.1167	34	197
595	0.1254	GO:0017171	serine hydrolase activity	0.1254	63	301
596	0.2140	GO:0071949	FAD binding	0.2140	1	3
597	0.1439	GO:0016853	isomerase activity	0.1439	53	253
598	0.1530	GO:0046906	tetrapyrrole binding	0.1530	8	42
599	0.1338	GO:0000150	recombinase activity	0.1338	28	162
600	0.2090	GO:0016881	acid-amino acid ligase activity	0.2453	6	18
		GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	0.1727	9	40
601	0.1087	GO:0003725	double-stranded RNA binding	0.1087	20	84
602	0.1580	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	0.1580	1	2
603	0.1351	GO:0015036	disulfide oxidoreductase activity	0.1651	39	206
		GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	0.1052	22	85
604	0.1408	GO:0003674	molecular_function	0.1408	5381	25017
605	0.1392	GO:0004896	cytokine receptor activity	0.1817	3	6
		GO:0004930	G-protein coupled receptor activity	0.0967	19	59
606	0.1329	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	0.1627	17	77
		GO:0004725	protein tyrosine phosphatase activity	0.1031	19	79
607	0.1284	GO:0016887	ATPase activity	0.1251	186	894
		GO:0042623	ATPase activity, coupled	0.1274	130	682
		GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.1258	600	2742
		GO:0017111	nucleoside-triphosphatase activity	0.1324	467	2242
		GO:0016462	pyrophosphatase activity	0.1311	503	2400
608	0.1880	GO:0010181	FMN binding	0.1880	4	36
609	0.1373	GO:0070568	guanylyltransferase activity	0.1373	16	63
610	0.0110	GO:0008446	GDP-mannose 4,6-dehydratase activity	0.0110	1	22
611	0.0449	GO:0008821	crossover junction endodeoxyribonuclease activity	0.0750	3	33
		GO:0004531	deoxyribonuclease II activity	0.0140	1	4
		GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters	0.0598	4	37
		GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters	0.0467	3	6
		GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity	0.0605	2	6
		GO:0016836	hydro-lyase activity	0.0135	2	36
612	0.1159	GO:0046983	protein dimerization activity	0.1159	47	185
613	0.0360	GO:0016859	cis-trans isomerase activity	0.0360	1	2
614	0.0700	GO:0016854	racemase and epimerase activity	0.0700	1	3
615	0.2035	GO:0070279	vitamin B6 binding	0.2035	4	30
616	0.0290	GO:0008879	glucose-1-phosphate thymidylyltransferase activity	0.0290	1	4
617	0.3830	GO:0004019	adenylosuccinate synthase activity	0.3830	1	19
618	0.1284	GO:0098772	molecular function regulator	0.1284	26	102
619	0.0060	GO:0031419	cobalamin binding	0.0060	1	23
620	0.1050	GO:0016209	antioxidant activity	0.1050	8	31
621	0.1534	GO:0046914	transition metal ion binding	0.1534	192	969
622	0.2470	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	0.2470	1	2
623	0.1125	GO:0004170	dUTP diphosphatase activity	0.1125	34	154
624	0.1586	GO:0016763	transferase activity, transferring pentosyl groups	0.1898	18	160
		GO:0016758	transferase activity, transferring hexosyl groups	0.1274	16	49
625	0.1580	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.1580	1	2
626	0.1955	GO:0008252	nucleotidase activity	0.1955	11	45
627	0.1823	GO:0004649	poly(ADP-ribose) glycohydrolase activity	0.1823	3	7
628	0.1373	GO:0097159	organic cyclic compound binding	0.1373	2999	14020
629	0.3359	GO:0034290	holin activity	0.3359	19	111
630	0.1148	GO:0016779	nucleotidyltransferase activity	0.1148	776	2918
631	0.1204	GO:0042624	ATPase activity, uncoupled	0.1204	36	104
632	0.1140	GO:0004482	mRNA (guanine-N7-)-methyltransferase activity	0.1140	51	195
633	0.1251	GO:0043168	anion binding	0.1251	1032	5223
634	0.1544	GO:0050660	flavin adenine dinucleotide binding	0.1792	44	311
		GO:0050662	coenzyme binding	0.1532	121	646
		GO:0051287	NAD binding	0.1457	10	41
		GO:0050661	NADP binding	0.1394	22	92
635	0.1229	GO:0008144	drug binding	0.1229	971	4796
636	0.1240	GO:0016597	amino acid binding	0.1240	1	3
637	0.0750	GO:0042802	identical protein binding	0.0750	5	29
638	0.2984	GO:0004609	phosphatidylserine decarboxylase activity	0.4780	1	3
		GO:0016832	aldehyde-lyase activity	0.1868	8	46
		GO:0016831	carboxy-lyase activity	0.2303	8	29
639	0.0866	GO:0008092	cytoskeletal protein binding	0.0866	5	11
640	0.0928	GO:0046982	protein heterodimerization activity	0.0928	4	23
641	0.1861	GO:0098518	polynucleotide phosphatase activity	0.1861	8	29
642	0.4050	GO:0003950	NAD+ ADP-ribosyltransferase activity	0.4050	1	2
643	0.1213	GO:0003684	damaged DNA binding	0.1213	3	9
644	0.1734	GO:0003964	RNA-directed DNA polymerase activity	0.2486	5	13
		GO:0003887	DNA-directed DNA polymerase activity	0.0982	228	812
645	0.1510	GO:0052796	exo-alpha-(2->8)-sialidase activity	0.1510	1	2
		GO:0052794	exo-alpha-(2->3)-sialidase activity	0.1510	1	2
		GO:0052795	exo-alpha-(2->6)-sialidase activity	0.1510	1	2
646	0.2723	GO:0008833	deoxyribonuclease IV (phage-T4-induced) activity	0.2723	18	73
647	0.1051	GO:0009378	four-way junction helicase activity	0.1060	1	2
		GO:0004003	ATP-dependent DNA helicase activity	0.1041	8	76
648	0.1027	GO:0060089	molecular transducer activity	0.1027	20	61
649	0.1119	GO:0005198	structural molecule activity	0.1119	592	2423
650	0.1440	GO:0003677	DNA binding	0.1440	1599	7503